Effect of denervation-induced muscle disuse on mitochondrial protein import.

@article{Singh2011EffectOD,
  title={Effect of denervation-induced muscle disuse on mitochondrial protein import.},
  author={Kaustabh Singh and David A. Hood},
  journal={American journal of physiology. Cell physiology},
  year={2011},
  volume={300 1},
  pages={C138-45}
}
This study determined whether muscle disuse affects mitochondrial protein import and whether changes in protein import are related to mitochondrial content and function. Protein import was measured using a model of unilateral peroneal nerve denervation in rats for 3 (n = 10), 7 (n = 12), or 14 (n = 14) days. We compared the import of preproteins into the matrix of subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondria isolated from the denervated and the contralateral control tibialis… CONTINUE READING

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