Effect of deep tissue incision on pH responses of afferent fibers and dorsal root ganglia innervating muscle.

@article{Kido2013EffectOD,
  title={Effect of deep tissue incision on pH responses of afferent fibers and dorsal root ganglia innervating muscle.},
  author={Kanta Kido and Mamta Gautam and Christopher J. Benson and He Gu and Timothy J. Brennan},
  journal={Anesthesiology},
  year={2013},
  volume={119 5},
  pages={1186-97}
}
BACKGROUND Understanding the mechanisms underlying deep tissue pain in the postoperative period is critical to improve therapies. Using the in vitro plantar flexor digitorum brevis muscle-nerve preparation and patch clamp recordings from cultured dorsal root ganglia neurons innervating incised and unincised muscle, the authors investigated responses to various pH changes. METHODS Incision including the plantar flexor digitorum brevis muscle or sham operation was made in the rat hind paw. On… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 41 references

TJ: simultaneous disruption of mouse AsiC1a, AsiC2 and AsiC3 genes enhances cutaneous mechanosensitivity

Kang s, Jang Jh, +5 authors Brennan
2012

simultaneous disruption of mouse AsiC 1 a , AsiC 2 and AsiC 3 genes enhances cutaneous mechanosensitivity

Kang s, Jang Jh, +5 authors TJ Brennan
Plos one • 2012

Acid-sensing ion channels in postoperative pain.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011

Tl: AsiC3 channels in multimodal sensory perception

WG li, Xu
ACs Chem Neurosci • 2011

sluka KA: selective targeting of AsiC3 using artificial miRNAs inhibits primary and secondary hyperalgesia after muscle inflammation

Walder Ry, M Gautam, Wilson sP, CJ Benson
2011

AsiC1 and AsiC3 play different roles in development of hyperalgesia following inflammatory muscle injury

Ry Walder, lA Rasmussen, +3 authors KA sluka
J Pain • 2010

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