Effect of cytochrome c on the phase behavior of charged multicomponent lipid membranes.

Abstract

We studied the effect of submicromolar concentrations of cytochrome c (cyt c) on the phase behavior of ternary lipid membranes composed of charged dioleoylphosphatidylglycerol, egg sphingomyelin and cholesterol. The protein was found to induce micron-sized domains in membranes belonging to the single-fluid-phase region of the protein-free ternary mixture… (More)
DOI: 10.1016/j.bbamem.2014.04.019

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