Effect of cysteinesulfinate on fatty acid-dependent uncoupling: modulation of recoupling by substrates of the aspartate/glutamate antiporter and diethyl pyrocarbonate.

Abstract

The action of cysteinesulfinate, the substrate of the aspartate/glutamate antiporter on the palmitate-induced uncoupling in rat liver mitochondria and the recoupling effect of glutamate, aspartate, and diethyl pyrocarbonate was studied. In the presence of palmitate and an inhibitor of the ADP/ATP-antiporter carboxyatractylate, cysteinesulfinate exerted a… (More)

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