Effect of cyclosporin A on spontaneous autoimmune thyroiditis of Obese strain (OS) chickens.

Abstract

The spontaneous autoimmune thyroiditis (SAT) which develops in the Obese strain (OS) of chickens depends on an intact B-dependent portion of immune system. T helper cells have been shown to be required for the production of thyroglobulin autoantibodies (Tg-AAb), but a possible contribution of cytotoxic T cells in the initial phases of SAT still remains to… (More)

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