Effect of cyclosporin A on proteinuria in the course of glomerulopathy associated with WT1 mutations

@inproceedings{Wasilewska2010EffectOC,
  title={Effect of cyclosporin A on proteinuria in the course of glomerulopathy associated with WT1 mutations},
  author={Anna Wasilewska and Elżbieta Kuroczycka-Saniutycz and Walentyna Zoch-Zwierz},
  booktitle={European Journal of Pediatrics},
  year={2010}
}
Denys–Drash syndrome (DDS) is characterized by progressive glomerulopathy caused by diffuse mesangial sclerosis (DMS), genitourinary defects, and a higher risk of developing Wilms’ tumor. It is commonly assumed that the DMS is unresponsive to any medications. In this report, we present a patient with Denys–Drash syndrome, in whom the cyclosporine A (CsA) was found to induce total remission. This observation and observations of other authors confirm that in genetic forms of nephrotic syndrome… CONTINUE READING

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