Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat.

@article{Agrawal2010EffectOC,
  title={Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat.},
  author={Rahul D Agrawal and Bhanvi Mishra and Ethika Tyagi and Chandishwar Nath and Rakesh Shukla},
  journal={Pharmacological research},
  year={2010},
  volume={61 3},
  pages={247-52}
}
Curcumin, the principal curcuminoid of turmeric, exhibits beneficial role in several neurodegenerative disorders such as dementia of Alzheimer type. Recent evidences suggest the involvement of brain insulin receptors (IRs) in the pathophysiology of dementia disorders. Therefore, the present study was undertaken to investigate the effect of curcumin on memory functions, brain IRs, acetylcholinesterase (AChE) activity and oxidative stress in intracerebroventricular (ICV) administered… CONTINUE READING

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