Effect of crocin on experimental atherosclerosis in quails and its mechanisms.

@article{He2005EffectOC,
  title={Effect of crocin on experimental atherosclerosis in quails and its mechanisms.},
  author={Shu-ying He and Zhi-Yu Qian and Fu-tian Tang and Na Wen and Guang-lin Xu and Liang Sheng},
  journal={Life sciences},
  year={2005},
  volume={77 8},
  pages={907-21}
}
In the present study, we examined the prophylaxis effect of crocin on experimental atherosclerosis and its possible mechanisms. The atherosclerosis formation was induced by hyperlipidamic diet in quails. At the 9th week, serum lipid, MDA and NO were measured, and HE staining was used to investigate the histopathological changes of aorta. Bovine aortic endothelial cells (EC) were obtained from the thoracic aorta of newborn calves. After incubation of the cells with Ox-LDL (50 mg x L(-1)) for 24… CONTINUE READING
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