Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients: a randomized, placebo-controlled 31P MRS study.

@article{Banerjee2010EffectOC,
  title={Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients: a randomized, placebo-controlled 31P MRS study.},
  author={Bidisha Banerjee and Uma R Sharma and Krithika Balasubramanian and M. S. Kalaivani and Veena Kalra and Naranamangalam Raghunathan Jagannathan},
  journal={Magnetic resonance imaging},
  year={2010},
  volume={28 5},
  pages={698-707}
}
Randomized, placebo-controlled single blinded study was carried out to evaluate the effect of oral creatine supplementation on cellular energetics, manual muscle test (MMT) score and functional status in steroid-naive, ambulatory boys suffering with Duchenne muscular dystrophy (DMD; n=33). Eighteen patients received creatine monohydrate (Cr; 5 g/day for 8 weeks), while 15 received placebo (500 mg of vitamin C). Phosphorus metabolite ratios were determined from the right calf muscle of patients… CONTINUE READING