Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children.

@article{Okada2003EffectOC,
  title={Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children.},
  author={Yasunori Okada and Makoto Shinohara and Tomio Kobayashi and Yoshinari Inoue and Takeshi Tomomasa and Tohru Kobayashi and A. Riki Y. Morikawa},
  journal={The Journal of pediatrics},
  year={2003},
  volume={143 3},
  pages={363-7}
}
OBJECTIVE The aim of this multicenter prospective and randomized study was to determine the effect of adding corticosteroids to intravenous gamma globulin (i.v.GG) therapy on serum cytokine levels, as well as to see its effect on the clinical course in children in the acute phase of Kawasaki disease (KD). STUDY DESIGN Patients with KD (n=32) were randomized to receive either i.v.GG alone (G group) or i.v.GG plus corticosteroids (G+S group). The clinical course and cytokine responses between… CONTINUE READING

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