Effect of controlled-release levodopa on the microstructure of sleep in Parkinson's disease.

Abstract

BACKGROUND Dopamine is an important neurotransmitter in the regulation of the sleep-wake cycle, and parkinsonian patients suffer from prominent sleep abnormalities. Hence, the question arises whether the disrupted sleep pattern in Parkinson's disease (PD) is responsive to dopaminergic treatment. METHODS Thirty-two patients (18 women, 45-82 years old; mean… (More)
DOI: 10.1111/j.1468-1331.2010.03213.x

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