Effect of conazole fungicides on reproductive development in the female rat.

@article{Rockett2006EffectOC,
  title={Effect of conazole fungicides on reproductive development in the female rat.},
  author={John C. Rockett and Michael G. Narotsky and Kary E. Thompson and Inthirany Thillainadarajah and Chad R. Blystone and Amber K. Goetz and Hongzu Ren and Deborah S. Best and Rachel N. Murrell and Harriette P. Nichols and Judith E. Schmid and D. Wolf and David J. Dix},
  journal={Reproductive toxicology},
  year={2006},
  volume={22 4},
  pages={647-58}
}
Three triazole fungicides were evaluated for effects on female rat reproductive development. Rats were exposed via feed to propiconazole (P) (100, 500, or 2500 ppm), myclobutanil (M) (100, 500, or 2000 ppm), or triadimefon (T) (100, 500, or 1800 ppm) from gestation day 6 to postnatal day (PND) 98. Body weight (BW) and anogenital distance (AGD) at PND 0, age and BW at vaginal opening (VO), estrous cyclicity, and body and organ weight at necropsy were measured. BW at PND 0 was unaffected by… CONTINUE READING