Effect of compressive loading on chondrocyte differentiation in agarose cultures of chick limb-bud cells.

@article{Elder2000EffectOC,
  title={Effect of compressive loading on chondrocyte differentiation in agarose cultures of chick limb-bud cells.},
  author={Steven H. Elder and James H. Kimura and Louis J Soslowsky and M A - Bionx Lavagnino and Steven A. N. Goldstein},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2000},
  volume={18 1},
  pages={78-86}
}
It is well established that mechanical loading is important to homeostasis of cartilage tissue, and growing evidence suggests that it influences cartilage differentiation as well. Whereas the effect of mechanical forces on chondrocyte biosynthesis and gene expression has been vigorously investigated, the effect of the mechanical environment on chondrocyte differentiation has received little attention. The long-term objective of this research is to investigate the regulatory role of mechanical… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Regulation of cartilage matrix metabolism by dynamic tissue shear strain

  • M JinMLevenston, E Prank, A Grodzinsky
  • Truns Orthop Res Soc
  • 1999

: Al - tercd aggrecan synthesis correlates with cell and nucleus srructurc in slatically compressed cartilage

  • Buschinann, EB Hunzikrr, YJ Kim, AJ Grodzinsky
  • J Cell Sci
  • 1996

The role of cartilage streaming potential : fluid flow and pressurc in the stimulation of chondrocyte biosynthesis during dynamic compression

  • Kim Y-J, LJ Bonassar, AJ Grodzinsky
  • JBionierh
  • 1995

Similar Papers

Loading similar papers…