Effect of compressional force on the crystallinity of directly compressible cellulose excipients.

@article{Kumar1999EffectOC,
  title={Effect of compressional force on the crystallinity of directly compressible cellulose excipients.},
  author={Vijay Kumar and Sanjeev H. Kothari},
  journal={International journal of pharmaceutics},
  year={1999},
  volume={177 2},
  pages={173-82}
}
The effect of compressional force on the crystallinity of low crystallinity cellulose (LCPC), microcrystalline celluloses (Avicel PH-101, PH-102 and PH-302 grades) and powdered cellulose (Solka Floc BW-100) has been investigated using an X-ray diffraction method. Microcrystalline and powdered celluloses showed an increase of about 10% in their crystallinities, compared to the values for the corresponding powders, at a compression pressure of 5-10 MPa. The increase in the crystallinity of LCPC… CONTINUE READING