Effect of combined therapy of diabinese and nicotinic acid on liver enzymes in rabbits with dithizone-induced diabetes

@article{Monago2010EffectOC,
  title={Effect of combined therapy of diabinese and nicotinic acid on liver enzymes in rabbits with dithizone-induced diabetes},
  author={Comfort C. Monago and Frank C. Onwuka and Erhabor Osaro},
  journal={Journal of Experimental Pharmacology},
  year={2010},
  volume={2},
  pages={145 - 153}
}
  • Comfort C. Monago, Frank C. Onwuka, Erhabor Osaro
  • Published 2010
  • Medicine, Chemistry
  • Journal of Experimental Pharmacology
  • The effects of diabinese, a known antidiabetic drug, and the combined effects of diabinese and nicotinic acid, a vitamin and antilipidemic drug, were studied in rabbits with dithizone-induced diabetes. Side effects of diabinese include hypoglycemia and liver toxicity. Dithizone was used to induce partial experimental diabetes and to increase blood glucose significantly (P < 0.05) by 31.3%, 23.5%, 19.5, 24.7%, and 23.9% in groups A (single therapy of diabinese 10 mg/kg body weight), B (10 mg of… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 60 REFERENCES

    Nicotinamide overload may play a role in the development of type 2 diabetes.

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