Effect of column temperature on enantioseparation of dihydropyrimidinones using alcohol solvated Chiralpak AS and AS-H columns.


In this study we report the application of column temperature programs to compare the chromatographic behaviors of four commercially available dihydropyrimidinone (DHP) compounds on Chiralpak AS and AS-H phases under different alcohol solvation conditions such as 1-propanol (1-PrOH), 2-methyl-1-PrOH (2-Me-1-PrOH), 1-butanol (1-BuOH), 2-BuOH, and tert-BuOH… (More)
DOI: 10.1002/jssc.200700482


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