Effect of coenzyme Q10 on mitochondrial respiratory proteins in trigeminal neuralgia

  title={Effect of coenzyme Q10 on mitochondrial respiratory proteins in trigeminal neuralgia},
  author={Chutikorn Khuankaew and Nattayaporn Apaijai and Passakorn Sawaddiruk and Thidarat Jaiwongkam and Sasiwan Kerdphoo and Surawut Pongsiriwet and Wichittra Tassaneeyakul and Nipon Chattipakorn and Siriporn C. Chattipakorn},
  journal={Free Radical Research},
  pages={415 - 425}
Abstract Trigeminal neuralgia (TN) is the neuropathic pain. Mitochondrial dysfunction, increased oxidative stress, and inflammation demonstrated in chronic pain. Carbamazepine (CBZ) is the first-line drug for TN, however, it is still insufficient. Coenzyme Q10 (CoQ10) has been used as the additional supplement for pain therapy. Nonetheless, mitochondrial respiratory proteins, oxidative stress, and inflammation in TN, and the add-on effects of CoQ10 on those defects have never been investigated… 

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  • S. Flatters
  • Biology, Medicine
    Progress in molecular biology and translational science
  • 2015

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