Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex.


Since a substantial proportion of smokers have comorbid mood disorders, the smoking cessation aid varenicline might occasionally be prescribed to patients who are simultaneously treated with antidepressants. Given that varenicline is a selective nicotinic acetylcholine receptor partial agonist and not a substrate or inhibitor of drug metabolizing enzymes… (More)
DOI: 10.1016/j.neuint.2010.10.015


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