Effect of co-administration of probiotics with polysaccharide based colon targeted delivery systems to optimize site specific drug release.

Abstract

Significant clinical success of colon targeted dosage forms has been limited by their inappropriate release profile at the target site. Their failure to release the drug completely in the colon may be attributed to changes in the colonic milieu because of pathological state, drug effect and psychological stress accompanying the diseased state or, a… (More)
DOI: 10.1016/j.ejpb.2015.09.012

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