Effect of clozapine and olanzapine on neutrophil kinetics: implications for drug-induced agranulocytosis.

Abstract

Clozapine is effective in the treatment of schizophrenia; however, its use is limited by a relatively high incidence of idiosyncratic agranulocytosis. The mechanism of clozapine-induced idiosyncratic agranulocytosis is unknown. Although most patients treated with clozapine do not develop agranulocytosis, most do have an immune response with an increase in… (More)
DOI: 10.1021/tx500183x

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Cite this paper

@article{Ng2014EffectOC, title={Effect of clozapine and olanzapine on neutrophil kinetics: implications for drug-induced agranulocytosis.}, author={Winnie Ng and Rossoune Kennar and Jack Uetrecht}, journal={Chemical research in toxicology}, year={2014}, volume={27 7}, pages={1104-8} }