Effect of clonidine on liver oxygen extraction during alcohol withdrawal in man.

@article{Hadengue1994EffectOC,
  title={Effect of clonidine on liver oxygen extraction during alcohol withdrawal in man.},
  author={Antoine Hadengue and Richard Moreau and Didier Lebrec and Christophe Gaudin and Bernard Rueff and J. P. Benhamou},
  journal={Journal of hepatology},
  year={1994},
  volume={20 2},
  pages={262-6}
}
Since catecholamines can alter splanchnic oxygen transport and extraction, the suppression of sympathetic overactivity during alcohol withdrawal might improve hepatic oxygen extraction. Therefore, this study investigated the effects of clonidine, a centrally-acting alpha 2-agonist which reduces sympathetic nervous outflow, on splanchnic oxygen transport and… CONTINUE READING