Effect of cilnidipine, a novel dihydropyridine Ca++-channel antagonist, on N-type Ca++ channel in rat dorsal root ganglion neurons.

@article{Fujii1997EffectOC,
  title={Effect of cilnidipine, a novel dihydropyridine Ca++-channel antagonist, on N-type Ca++ channel in rat dorsal root ganglion neurons.},
  author={Shiroh Fujii and Kohji Kameyama and Masamichi Hosono and Yukio Hayashi and Kenji Kitamura},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1997},
  volume={280 3},
  pages={1184-91}
}
We investigated the effects of cilnidipine, a dihydropyridine derivative, on neuronal Ca++ channels in rat dorsal root ganglion neurons. Voltage-dependent Ca++-channel currents were recorded, using 5 mM Ba++ as the charge carrier, by means of the whole-cell patch-clamp technique. The Ba++ current was subdivided pharmacologically into calciseptine-sensitive… CONTINUE READING