Effect of chronic unpredictable mild stress on brain-pancreas relative protein in rat brain and pancreas.

@article{Lin2005EffectOC,
  title={Effect of chronic unpredictable mild stress on brain-pancreas relative protein in rat brain and pancreas.},
  author={Yan-hua Lin and Ai-hua Liu and Ying Xu and Lu Tie and He-ming Yu and Xue-Jun Li},
  journal={Behavioural brain research},
  year={2005},
  volume={165 1},
  pages={63-71}
}
Brain-pancreas relative protein (BPRP) is a novel protein whose biological function remains unknown. Here, we report a possible role of BPRP in male rats exposed to chronic unpredictable mild stress (CUMS) to induce depression for 3 weeks. Compared to unstressed rats, those exposed to CUMS showed significantly less weight gain with age, decreased consumption of (and preference for) sucrose without a change in total fluid consumption. Exposure to CUMS significantly reduced open-field exploration… CONTINUE READING
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