Effect of chronic treatment with Rosiglitazone on Leydig cell steroidogenesis in rats: In vivo and ex vivo studies

@inproceedings{Couto2010EffectOC,
  title={Effect of chronic treatment with Rosiglitazone on Leydig cell steroidogenesis in rats: In vivo and ex vivo studies},
  author={Jana{\'i}na de Albuquerque Couto and Karina L A Saraiva and Cleiton Diniz Barros and Daniel Pedro Udrisar and Christina Alves Peixoto and Juliany S B C{\'e}sar Vieira and Maria do Carmo Alves de Lima and Suely Lins Galdino and Ivan da R. Pitta and Maria In{\^e}s Wanderley},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2010}
}
BACKGROUND The present study was designed to examine the effect of chronic treatment with rosiglitazone - thiazolidinedione used in the treatment of type 2 diabetes mellitus for its insulin sensitizing effects - on the Leydig cell steroidogenic capacity and expression of the steroidogenic acute regulatory protein (StAR) and cholesterol side-chain cleavage… CONTINUE READING