Effect of chronic hypoxia on calcium signalling in airway smooth muscle cells.

@article{Belouchi1999EffectOC,
  title={Effect of chronic hypoxia on calcium signalling in airway smooth muscle cells.},
  author={N E Belouchi and Etienne Roux and J. P. Savineau and Roger Marthan},
  journal={The European respiratory journal},
  year={1999},
  volume={14 1},
  pages={74-9}
}
Chronic hypoxia (CH) alters smooth muscle contractility. CH generally produces a sustained attenuation of vasoreactivity. In airways, this effect of CH is poorly understood although CH is frequently observed in patients with pulmonary diseases. This study was designed to examine the effect of CH on both the isometric contraction of isolated rings and the cytosolic calcium concentration ([Ca2+]i) using microspectrofluorimetry in freshly isolated cells from rat tracheal smooth muscle. Tissues… CONTINUE READING

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