• Medicine
  • Published in Cancer research 1958

Effect of chronic exposure to fast neutrons on the development of mammary tumors in the rat.

@article{Hartwig1958EffectOC,
  title={Effect of chronic exposure to fast neutrons on the development of mammary tumors in the rat.},
  author={Quentin L. Hartwig and Sidney P. Kent and John A. Sproul},
  journal={Cancer research},
  year={1958},
  volume={18 6},
  pages={
          736-9
        }
}
Summary Fifty Sprague-Dawley rats were chronically exposed for 6 months to 154 rep of fast neutrons delivered at a dose rate of 87.2 mrep/hour, and 50 served as controls. Sixty-eight per cent of the irradiated rats developed one or more tumors, as compared with 14 per cent in the controls. Malignant tumors were found in 32 per cent (11/34) of the irradiated rats with tumors, 36 per cent (4/11) of which had metastasized. No metastasis occurred in the controls. Most of the tumors in the… CONTINUE READING

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