Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration.

@article{Belinsky1982EffectOC,
  title={Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration.},
  author={Steven Alan Belinsky and Mary A Bedell and James A. Swenberg},
  journal={Carcinogenesis},
  year={1982},
  volume={3 11},
  pages={1293-7}
}
Chronic alcohol ingestion has been associated with human cancer of the larynx, esophagus, and liver, however the mechanism(s) of ethanol's interaction in either initiation and/or progression of cancer is unknown. The initiation of chemical carcinogenesis is thought to involve an alteration of the DNA which becomes fixed in the daughter strand following the… CONTINUE READING