Effect of chronic T-2 toxin exposure in rabbit bucks, determination of the No Observed Adverse Effect Level (NOAEL).

@article{Kovcs2013EffectOC,
  title={Effect of chronic T-2 toxin exposure in rabbit bucks, determination of the No Observed Adverse Effect Level (NOAEL).},
  author={Melinda Kov{\'a}cs and G{\'a}bor Tornyos and Zsolt Matics and M M{\'e}zes and Kriszti{\'a}n Balogh and Veronika Rajli and Zs{\'o}fia Bloch-Bodn{\'a}r and Mikl{\'o}s Rusvai and M{\'i}ra M{\'a}ndoki and S{\'a}ndor Cseh},
  journal={Animal reproduction science},
  year={2013},
  volume={137 3-4},
  pages={245-52}
}
T-2 toxin (T-2) was administered to adult Pannon White (n = 10/group) male rabbits for 65 days, first in a suspension by gavage (0.05, 0.1 or 0.2 mg/animal/day), and secondly mixed into the feed (0.33 and 0.66 mg/kg feed). In the first experiment 0.1 mg T-2 exposure resulted in temporary decrease in feed intake, slower increase in the gonadotropin-releasing hormone (GnRH) induced testosterone synthesis, slight centrolobular infiltration in the liver and a slight hyperplasia of the Leydig cells… CONTINUE READING