Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries.

@article{Michel1994EffectOC,
  title={Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries.},
  author={J B Michel and Didier Heudes and Odile Michel and Pierre Poitevin and Monique Philippe and Elizabeth Scalbert and Bruno Corman and Bernard I L{\'e}vy},
  journal={The American journal of physiology},
  year={1994},
  volume={267 1 Pt 2},
  pages={R124-35}
}
The consequences of hypertension and aging on cardiovascular structure and function are reputed to be similar, suggesting that blood pressure plays a role in the aging process. However, the exact relationship between aging, blood pressure, and the arterial structure-function relationship has not been demonstrated. To test the effects of aging, renin-angiotensin system, and pressure on the arterial wall, 20 normotensive male WAG/Rij rats were killed at 6, 12, 24, and 30 mo of age and compared… CONTINUE READING

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