Effect of chondroitin sulphate on material properties and bone remodelling around hydroxyapatite/collagen composites.

@article{Schneiders2008EffectOC,
  title={Effect of chondroitin sulphate on material properties and bone remodelling around hydroxyapatite/collagen composites.},
  author={Wolfgang Schneiders and Antje Reinstorf and Michael Ruhnow and Sebastian Rehberg and Jan Heineck and Irene Hinterseher and Achim Biewener and Hans Zwipp and Stefan Rammelt},
  journal={Journal of biomedical materials research. Part A},
  year={2008},
  volume={85 3},
  pages={
          638-45
        }
}
Chondroitin sulphate (CS) has an anti-inflammatory effect and increases the regeneration ability of injured bone. The goal of this study was to characterize the material properties and osteoconductive potency of calcium phosphate bone cements modified with CS. The early interface reaction of cancellous bone to a nanokristalline hydroxyapatite cement containing type I collagen (HA/Coll) without and with CS (HA/Coll/CS) in a rat tibia model was evaluated. Cylindrical implants were inserted press… CONTINUE READING

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