Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver.

Abstract

Choline and C1 metabolism pathways intersect at the formation of methionine from homocysteine. Hepatic S-adenosylmethionine (AdoMet) concentrations are decreased in animals ingesting diets deficient in choline, and it has been suggested that this occurs because the availability of methionine limits AdoMet synthesis. If the above hypothesis is correct… (More)

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@article{Zeisel1989EffectOC, title={Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver.}, author={Steven H Zeisel and Tracey Zola and Kerry Ann daCosta and Elizabeth Anne Pomfret}, journal={The Biochemical journal}, year={1989}, volume={259 3}, pages={725-9} }