Effect of chlorpromazine on enzymic oxidation of lipids


Chlorpromazine was found to inhibit enzymic NADPH-dependent peroxidation of lipids in rat liver microsomes. The inhibitory effect was shown to be due to: 1) the antioxidant action of hydroxy derivatives of chlorpromazine produced in the course of its metabolism by NADPH-dependent microsomal oxygenases; 2) competition for reduced components of electron… (More)
DOI: 10.1007/BF00805891


1 Figure or Table

Cite this paper

@article{Eluashvili2004EffectOC, title={Effect of chlorpromazine on enzymic oxidation of lipids}, author={I. A. Eluashvili and T. P. Pashinova and Elizaveta Dmitrievna Bogdanova and Valerian E Kagan and Leonid L Prilipko}, journal={Bulletin of Experimental Biology and Medicine}, year={2004}, volume={84}, pages={1302-1306} }