Effect of chitosan malate on viability and cytoskeletal structures morphology of Caco-2 cells.

@article{Juliano2011EffectOC,
  title={Effect of chitosan malate on viability and cytoskeletal structures morphology of Caco-2 cells.},
  author={Claudia Juliano and Grazia Galleri and Therese Klemetsrud and Jan Karlsen and Paolo Giunchedi},
  journal={International journal of pharmaceutics},
  year={2011},
  volume={420 2},
  pages={
          223-30
        }
}
The aim of this work was to evaluate the effects of the treatment with chitosan malate (CM) on viability of Caco-2 cells and on the morphology and the integrity of their cytoskeletal structures (microtubules, microfilaments). Cytotoxicity of CM, both as a solution and as microparticles obtained by spray drying, was evaluated by using the reduction of MTT reagent; microtubule and microfilaments organization of Caco-2 cells treated with CM solution was examined with immunofluorescence techniques… 
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