Effect of chitosan feeding on intestinal bile acid metabolism in rats

@article{Fukada2006EffectOC,
  title={Effect of chitosan feeding on intestinal bile acid metabolism in rats},
  author={Yasuhiko Fukada and Koji Kimura and Yoshikazu Ayaki},
  journal={Lipids},
  year={2006},
  volume={26},
  pages={395-399}
}
The effect of chitosan feeding (for 21 days) on intestinal bile acids was studied in male rats. Serum cholesterol levels in rats fed a commercial diet low in cholesterol were decreased by chitosan supplementation. Chitosan inhibited the transformation of cholesterol to coprostanol without causing a qualitative change in fecal excretion of these neutral sterols. Increased fiber consumption did not increase fecal excretion of bile acids, but caused a marked change in fecal bile acid composition… 
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