Effect of chemokine receptor CX3CR1 deficiency in a murine model of respiratory syncytial virus infection.

@article{Johnson2012EffectOC,
  title={Effect of chemokine receptor CX3CR1 deficiency in a murine model of respiratory syncytial virus infection.},
  author={Crystal H. Johnson and Congrong Miao and Elisabeth G. Blanchard and Hayat Caidi and Gertrud U Radu and Jennifer L Harcourt and Lia M. Haynes},
  journal={Comparative medicine},
  year={2012},
  volume={62 1},
  pages={
          14-20
        }
}
Respiratory syncytial virus (RSV) is the most common cause of serious lower respiratory illness in infants and young children worldwide, making it a high priority for development of strategies for prevention and treatment. RSV can cause repeat infections throughout life, with serious complications in elderly and immunocompromised patients. Previous studies indicate that the RSV G protein binds through a CX3C chemokine motif to the host chemokine receptor, CX3CR1, and modulates the inflammatory… CONTINUE READING