Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.

@article{Guido1992EffectOC,
  title={Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.},
  author={Shoba Guido and Thangam Joseph},
  journal={Indian journal of experimental biology},
  year={1992},
  volume={30 4},
  pages={292-4}
}
Different classes of calcium antagonists, viz. verapamil (diphenylalkylamine), diltiazem (benzothiazepine), nifedipine, felodipine and nimodipine (dihydropyridines), were examined for their effects on lipid profile in rats. Clofibrate was the reference standard. Clofibrate significantly prevented the rise of serum triglycerides and total cholesterol produced by high fat diet and raised antiatherogenic index to 1.6 times than that of high fat diet controls. Of the calcium antagonists studied… CONTINUE READING

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