Effect of chemical modifications on allergenic potency of peanut proteins.


BACKGROUND Modification of native peanut extracts could reduce adverse effects of peanut immunotherapy. OBJECTIVE We sought to compare native and chemically modified crude peanut extract (CPE) and major peanut allergens Ara h 2 and Ara h 6 in a mediator-release assay based on the rat basophilic leukemia (RBL) cell line transfected with human Fcε receptor… (More)
DOI: 10.2500/aap.2015.36.3840


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