Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial1234

@inproceedings{Jebb2010EffectOC,
  title={Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial1234},
  author={Susan A Jebb and Julie A Lovegrove and Bruce A. Griffin and Gary S. Frost and Carmel S. Moore and Mark D. Chatfield and Les J Bluck and C. S. Williams and Thomas A. B. Sanders},
  booktitle={The American journal of clinical nutrition},
  year={2010}
}
BACKGROUND Insulin sensitivity (Si) is improved by weight loss and exercise, but the effects of the replacement of saturated fatty acids (SFAs) with monounsaturated fatty acids (MUFAs) or carbohydrates of high glycemic index (HGI) or low glycemic index (LGI) are uncertain. OBJECTIVE We conducted a dietary intervention trial to study these effects in participants at risk of developing metabolic syndrome. DESIGN We conducted a 5-center, parallel design, randomized controlled trial [RISCK… CONTINUE READING