Effect of centrally acting drugs on the uptake of γ‐aminobutyric acid (GABA) by slices of rat cerebral cortex

@article{Harris1973EffectOC,
  title={Effect of centrally acting drugs on the uptake of $\gamma$‐aminobutyric acid (GABA) by slices of rat cerebral cortex},
  author={M. Harris and J. Hopkin and M. Neal},
  journal={British Journal of Pharmacology},
  year={1973},
  volume={47}
}
1 The effects of centrally acting drugs on the uptake of 3H‐γ‐aminobutyric acid (GABA) by slices of rat cerebral cortex have been studied. 2 Many centrally acting drugs at concentrations of 0·1–1·0 mm significantly inhibited the uptake of 3H‐GABA by cortical slices, but the only classes of drugs in which all members consistently produced inhibition of uptake were the phenothiazines, tricyclic antidepressants, and butyrophenones. 3 The receptor blocking drugs; phentolamine, propranolol… Expand
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