Effect of central administration of interleukin-1 receptor antagonist on protein synthesis in skeletal muscle, kidney, and liver during sepsis.

@article{Lloyd2003EffectOC,
  title={Effect of central administration of interleukin-1 receptor antagonist on protein synthesis in skeletal muscle, kidney, and liver during sepsis.},
  author={Carolyn E Lloyd and Mary Palopoli and Thomas C. Vary},
  journal={Metabolism: clinical and experimental},
  year={2003},
  volume={52 9},
  pages={1218-25}
}
Inflammatory cytokines may mediate the host response to infection via central nervous system (CNS), endocrine, and/or paracrine pathways. The purpose of the present study was to determine whether intracerebroventricular (ICV) infusion of interleukin-1 receptor antagonist (IL-1ra) influences the effects of sepsis on protein metabolism in peripheral organs… CONTINUE READING