Corpus ID: 35156572

Effect of catecholamines and beta-blockers on linoleic acid desaturation activity.

@article{Gmez1978EffectOC,
  title={Effect of catecholamines and beta-blockers on linoleic acid desaturation activity.},
  author={I. N. de G{\'o}mez and M. J. D. de Alaniz and R. Brenner},
  journal={Lipids},
  year={1978},
  volume={13 10},
  pages={
          649-52
        }
}
  • I. N. de Gómez, M. J. D. de Alaniz, R. Brenner
  • Published 1978
  • Medicine
  • Lipids
  • The effect of catecholamines and adrenergic blocking agents on the oxidative desaturation of linoleic acid in rat liver microsomes was studied. Epinephrine (1 mg/kg/body weight) produced a significant decrease on the conversion of [1-14C]linoleic acid to gamma-linolenic acid. The effect of epinephrine was blocked by single injections of the beta blockers propranolol (10 mg/kg body weight) or dichloroisoproterenol 30 min before the hormone treatment. Isoproterenol (100 microgram/kg body weight… CONTINUE READING