Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures.

@article{Islam2004EffectOC,
  title={Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures.},
  author={Nazrul Islam and Peter N Stewart and Ian Larson and Patrick G Hartley},
  journal={Journal of pharmaceutical sciences},
  year={2004},
  volume={93 4},
  pages={1030-8}
}
The objective of this study was to determine the influence of lactose carrier size on drug dispersion of salmeterol xinafoate (SX) from interactive mixtures. SX dispersion was measured by using the fine particle fractions determined by a twin stage impinger attached to a Rotahaler. The particle size of the lactose carrier in the SX interactive mixtures was varied using a range of commercial inhalation-grade lactoses. In addition, differing size fractions of individual lactose samples were… CONTINUE READING

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