Effect of carnitine on decrease of branched chain amino acids and glutamine in serum of septic rats.

@article{Hayashi1996EffectOC,
  title={Effect of carnitine on decrease of branched chain amino acids and glutamine in serum of septic rats.},
  author={Naoki Hayashi and Daiji Yoshihara and Norio Kashiwabara and Yasuyoshi Takeshita and Harumi Handa and Mitsuru Yamakawa},
  journal={Biological \& pharmaceutical bulletin},
  year={1996},
  volume={19 1},
  pages={
          157-9
        }
}
Blood concentrations of branched chain amino acids (BCAA; leucine, isoleucine, and valine) and glutamine (Gln) decrease markedly in sepsis. We investigated the effect of carnitine on serum concentrations of BCAA and Gln in fasted septic rats. Rats were made septic by cecal ligation and puncture. They developed extremely high blood concentrations of endotoxin, and serum concentrations of BCAA and Gln were markedly decreased 2 d after the operation. When L-carnitine was administered… 
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Branched‐chain amino acids

The branched‐chain amino acids, isoleucine, leucine and valine, are unique in that they are principally metabolized extrahepatically in the skeletal muscle, but the resulting studies have not demonstrated a clear clinical benefit for BCAA nutritional supplements.

Mechanisms responsible for regulation of branched-chain amino acid catabolism.

Dietary L-carnitine and energy and lipid metabolism in African catfish (Clarias gariepinus) juveniles

The aim of this study was to assess the effects of dietary L-Carnitine on lipid metabolism in African catfish, and to determine whether dietary carnitine effects on fish performance is associated to fish size and/or dietary protein to non-protein ratios.

Branched-chain amino acid-enriched nutritional support in surgical and cancer patients.

The role of BCAAs in the nutritional support of stressed surgical and cancer patients remains to be clearly defined, despite their potential beneficial biological properties.

Changes in amino acid composition in the tissues of African catfish (Clarias gariepinus) as a consequence of dietary L-carnitine supplements

Dietary L-carnitine supplementation may increase fatty acid oxidation and possibly decrease amino acid combustion for energy in the African catfish.

Branched-Chain Amino Acids : Metabolism , Physiological Function , and Application Branched-Chain Amino Acid-Enriched Nutritional Support in Surgical and Cancer Patients 1 , 2

The role of BCAAs in the nutritional support of stressed surgical and cancer patients remains to be clearly defined, despite their potential beneficial biological properties.

Intermediate metabolism in association with the amino acid profile during the third trimester of normal pregnancy and diet-controlled gestational diabetes.

Effects on the Human Body of a Dietary Supplement Containing L-Carnitine and Garcinia cambogia Extract: A Study using Double-blind Tests

The findings suggest that the consumption of the supplement can reduce the oxidative damage; however, the effect on QOL was equivocal.

Leucine-induced activation of translational initiation is partly regulated by the branched-chain alpha-keto acid dehydrogenase complex in C2C12 cells.

Carnitine Deficiency: Primary and Secondary Syndromes

It is shown that carnitine deficiency may be frequently recognized in human and the list of disorders associated with carnitines deficiency is growing.