Effect of captopril on the prevention and regression of myocardial cell hypertrophy and interstitial fibrosis in pressure overload cardiac hypertrophy.

@article{Rossi1992EffectOC,
  title={Effect of captopril on the prevention and regression of myocardial cell hypertrophy and interstitial fibrosis in pressure overload cardiac hypertrophy.},
  author={Marcos Ant{\^o}nio Rossi and Luiz C{\'e}sar Peres},
  journal={American heart journal},
  year={1992},
  volume={124 3},
  pages={700-9}
}
This article reports on the effects of captopril on both the prevention and the regression of myocardial cell hypertrophy and interstitial fibrosis in experimental animals (rats) with pressure overloaded hearts. Constriction of the abdominal aorta just below the diaphragm during periods of 20 days (prevention experiment) and 40 days (regression experiment) resulted in hypertension and cardiac hypertrophy. In the prevention experiment, captopril was able to inhibit the development of high blood… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Cardiac Fibrosis and Heart Failure: Cause or Effect?

Advances in Biochemistry in Health and Disease • 2015
View 9 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…