Effect of capsaicin treatment on nociceptors in rat glabrous skin one day after plantar incision.

@article{Kang2010EffectOC,
  title={Effect of capsaicin treatment on nociceptors in rat glabrous skin one day after plantar incision.},
  author={Sinyoung Kang and Chaoran Wu and Ratan K Banik and Timothy J. Brennan},
  journal={Pain},
  year={2010},
  volume={148 1},
  pages={128-40}
}
Dilute capsaicin produces a differential effect on incision-related pain behaviors depending upon the test; it reduces heat hyperalgesia and guarding pain but not mechanical hyperalgesia. This suggests that common mechanisms for heat hyperalgesia and guarding pain occur, and distinct mechanisms exist for mechanical hyperalgesia. The purpose of the present study was to evaluate the effect of capsaicin treatment on the activity of cutaneous nociceptors sensitized by incision to understand the… CONTINUE READING
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