Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials.

@article{Bilous2009EffectOC,
  title={Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials.},
  author={Rudy W. Bilous and Nishi Chaturvedi and Anne Katrin Sj{\o}lie and JohnH. Fuller and Ronald Klein and Trevor J Orchard and Massimo Porta and Henrik Parving},
  journal={Annals of internal medicine},
  year={2009},
  volume={151 1},
  pages={
          11-20, W3-4
        }
}
BACKGROUND Microalbuminuria in diabetes is strongly predictive of nephropathy, end-stage renal disease, and premature cardiovascular morbidity and mortality. Effective preventive therapies are therefore a clinical priority. OBJECTIVE To determine whether the angiotensin-receptor blocker candesartan compared with placebo affects microalbuminuria incidence or rate of change in albuminuria in type 1 and type 2 diabetes. DESIGN 3 randomized trials of the DIRECT (Diabetic Retinopathy Candesartan… CONTINUE READING

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