Effect of cancer-related and drug-induced alterations in surface carbohydrates on the invasive capacity of mouse and rat cells.

@article{Bolscher1986EffectOC,
  title={Effect of cancer-related and drug-induced alterations in surface carbohydrates on the invasive capacity of mouse and rat cells.},
  author={Jan G. M. Bolscher and Denis C. C. Schallier and Lou A. Smets and H K van Rooy and John G. Collard and Eric A. Bruyneel and Marc M. K. Mareel},
  journal={Cancer research},
  year={1986},
  volume={46 8},
  pages={4080-6}
}
The effect of alterations in cell surface carbohydrates on invasion of mouse and rat cells into embryonic chick heart fragments in organ culture was studied. Matching pairs of malignant and nonmalignant cells, including all categories of carcinogenic induction (i.e., viral, chemical, or oncogenic), were compared for their alterations in cell surface carbohydrates and invasive behavior. Glycopeptides derived from the surface of malignant cells expressed cancer-related changes in carbohydrate… CONTINUE READING