Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly(propylene fumarate) scaffolds.

@article{Dadsetan2015EffectOC,
  title={Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly(propylene fumarate) scaffolds.},
  author={Mahrokh Dadsetan and Teja Guda and Maximilian Walter Runge and Dindo Q. Mijares and Racquel Z Legeros and J. P. Legeros and David T Silliman and Lichun Lu and Joseph C. Wenke and Pamela R Brown Baer and Michael J. Yaszemski},
  journal={Acta biomaterialia},
  year={2015},
  volume={18},
  pages={
          9-20
        }
}
Various calcium phosphate based coatings have been evaluated for better bony integration of metallic implants and are currently being investigated to improve the surface bioactivity of polymeric scaffolds. The aim of this study was to evaluate the role of calcium phosphate coating and simultaneous delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the in vivo bone regeneration capacity of biodegradable, porous poly(propylene fumarate) (PPF) scaffolds. PPF scaffolds were… CONTINUE READING
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