Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects.

@article{Noguchi2015EffectOC,
  title={Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects.},
  author={Katsuhiko Noguchi and Toshihiro Matsuzaki and Mayuko Sakanashi and Naobumi Hamadate and Taro Uchida and Mika Kina-Tanada and Haruaki Kubota and Junko Nakasone and Matao Sakanashi and Shinichiro Ueda and Hiroaki Masuzaki and Shogo Ishiuchi and Yusuke Ohya and Masato Tsutsui},
  journal={Journal of pharmacological sciences},
  year={2015},
  volume={127 2},
  pages={
          217-22
        }
}
Recent epidemiological studies have demonstrated that coffee drinking is associated with reduced mortality of cardiovascular disease. However, its precise mechanisms remain to be clarified. In this study, we examined whether single ingestion of caffeine contained in a cup of coffee improves microvascular function in healthy subjects. A double-blind, placebo-controlled, crossover study was performed in 27 healthy volunteers. A cup of either caffeinated or decaffeinated coffee was drunk by the… CONTINUE READING
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