Effect of cadmium on bromosulfophthalein kinetics in the isolated perfused rat liver system.

@article{Soto2002EffectOC,
  title={Effect of cadmium on bromosulfophthalein kinetics in the isolated perfused rat liver system.},
  author={Armando Soto and Brent D. Foy and John M. Frazier},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2002},
  volume={69 2},
  pages={460-9}
}
Bromosulfophthalein (BSP) is a relatively nontoxic organic anion used as an in vivo indicator of liver performance. Elimination of BSP via the biliary system following iv injection requires dissociation from albumin in plasma, translocation across the sinusoidal membrane, conjugation with glutathione within the hepatocyte, translocation across the bile… CONTINUE READING